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C Reactive Protein (CRP)

C-RP; PTX1; Pentraxin-Related; Pentraxin 1

C-reactive protein is a liver-derived pattern recognition molecule that is increased in inflammatory states. It rapidly increases within hours after tissue injury, and it is suggested that it is part of the innate immune system and contributes to host defense. Since cardiovascular disease is at least in part an inflammatory process, CRP has been investigated in the context of arteriosclerosis and subsequent vascular disorders. Based on multiple epidemiological and intervention studies, minor CRP elevation has been shown to be associated with future major cardiovascular risk.CRP is known for several decades as a nonspecific inflammation marker. High CRP levels are detected in human blood during bacterial, viral and other infections, as well as in noninfectious diseases such as rheumatic disorders and malignancies.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Hu01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Hu01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Hu01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Hu01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Hu01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Mu01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Mu01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Mu01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Mu01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Mu01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Ra01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Ra01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Ra01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Ra01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Ra01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Ca01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Ca01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Ca01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Ca01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Ca01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Po01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Po01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Po01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Po01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Po01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Bo01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Bo01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Bo01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Bo01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Bo01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Rb01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Rb01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Rb01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Rb01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Rb01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV990Mo01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV990Mo01 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAV990Mo01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
Assay Kits CLV990Mo01 CLIA Kit for C Reactive Protein (CRP) CLIA assay for Antigen Detection
ELV990Mo01 ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Genomic DNA sequence for human C-reactive protein."
J. Biol. Chem. 260:13377-13383(1985) [PubMed] [Europe PMC] [Abstract]

"Characterization of genomic and complementary DNA sequence of human C-reactive protein, and comparison with the complementary DNA sequence of serum amyloid P component."
J. Biol. Chem. 260:13384-13388(1985) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Biosynthesis and postsynthetic processing of human C-reactive protein."
J. Immunol. 131:2416-2419(1983) [PubMed] [Europe PMC] [Abstract]

"Isolation of human C-reactive protein complementary DNA and localization of the gene to chromosome 1."
Science 221:69-71(1983) [PubMed] [Europe PMC] [Abstract]

"Primary structure of human C-reactive protein."
J. Biol. Chem. 254:489-502(1979) [PubMed] [Europe PMC] [Abstract]

"Partial amino-acid sequences of human and rabbit C-reactive proteins: homology with immunoglobulins and histocompatibility antigens."
Proc. Natl. Acad. Sci. U.S.A. 74:1214-1218(1977) [PubMed] [Europe PMC] [Abstract]

"Selected expression profiling of full-length proteins and their variants in human plasma."
Clin. Proteomics 1:7-16(2004)

"Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense."
J. Immunol. 185:6899-6910(2010) [PubMed] [Europe PMC] [Abstract]

"Comparative analyses of pentraxins: implications for protomer assembly and ligand binding."
Structure 2:1017-1027(1994) [PubMed] [Europe PMC] [Abstract]

"Three dimensional structure of human C-reactive protein."
Nat. Struct. Biol. 3:346-353(1996) [PubMed] [Europe PMC] [Abstract]

"The physiological structure of human C-reactive protein and its complex with phosphocholine."
Structure 7:169-177(1999) [PubMed] [Europe PMC] [Abstract]