Prolactin (PRL)
LTH; Luteotropic Hormone
Luteotropic hormone is a peptide hormone discovered by Dr. Henry Friesen, primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed. Oxytocin, another hormone, is also released, which triggers milk let-down.Prolactin (PRL) is a peptide hormone primarily associated with lactation. In breastfeeding, the infant suckling the teat stimulates the production of prolactin, which fills the breast with milk (lactogenesis) in preparation for the next feed. Oxytocin, a similar hormone, is also released, which triggers milk let-down. Prolactin (PRL) is a polypeptide hormone secreted by anterior pituitary of both male and female.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Hu01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Hu01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Hu01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Hu01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Hu01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Mu01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Mu01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Mu01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Mu01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Mu01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Ra01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Ra01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Ra01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Ra01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Ra01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Ca01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Ca01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Ca01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Ca01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Ca01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Po01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Po01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Po01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Po01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Po01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Bo01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Bo01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Bo01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Bo01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Bo01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Rb01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Rb01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Rb01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Rb01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Rb01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV965Mo01 | Recombinant Prolactin (PRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV965Mo01 | Monoclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IP. |
PAV965Mo01 | Polyclonal Antibody to Prolactin (PRL) | WB; IHC; ICC; IF. | |
Assay Kits | CLV965Mo01 | CLIA Kit for Prolactin (PRL) | CLIA assay for Antigen Detection |
ELV965Mo01 | ELISA Kit for Prolactin (PRL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"Isolation and characterization of the human prolactin gene."
EMBO J. 3:429-437(1984) [PubMed] [Europe PMC] [Abstract]
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"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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"Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing."
Breast Cancer Res. Treat. 44:243-253(1997) [PubMed] [Europe PMC] [Abstract]
"Human pituitary prolactin (hPRL): the entire linear amino acid sequence."
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"High sensitivity automated sequence determination of polypeptides."
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J. Clin. Endocrinol. Metab. 90:3036-3044(2005) [PubMed] [Europe PMC] [Abstract]
"The tertiary structure and backbone dynamics of human prolactin."
J. Mol. Biol. 328:1105-1121(2003) [PubMed] [Europe PMC] [Abstract]
"Solution structure of human prolactin."
J. Mol. Biol. 351:810-823(2005) [PubMed] [Europe PMC] [Abstract]
"Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL."
J. Biol. Chem. 282:33118-33131(2007) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor."
J. Biol. Chem. 283:19085-19094(2008) [PubMed] [Europe PMC] [Abstract]