Synuclein Gamma (SNCg)
SNC-G; gSYN; SR; BCSG1; PERSYN; PRSN; Breast Cancer Specific Protein 1; Persyn; Synoretin
Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Gamma-synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, and in the olfactory epithelium. Gamma-synuclein is the least conserved of the synuclein proteins.Gamma-Synucleins expression in breast tumors is a marker for tumor progression as mammalian gamma-synuclein was first identified as breast cancer-specific gene 1 (BCSG1).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Hu01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Hu01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Hu01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Hu01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Hu01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Mu01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Mu01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Mu01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Mu01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Mu01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Ra01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Ra01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Ra01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Ra01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Ra01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Ca01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Ca01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Ca01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Ca01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Ca01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Po01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Po01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Po01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Po01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Po01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Bo01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Bo01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Bo01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Bo01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Bo01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Rb01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Rb01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Rb01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Rb01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Rb01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV872Mo01 | Recombinant Synuclein Gamma (SNCg) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV872Mo01 | Monoclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IP. |
| PAV872Mo01 | Polyclonal Antibody to Synuclein Gamma (SNCg) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV872Mo01 | CLIA Kit for Synuclein Gamma (SNCg) | CLIA assay for Antigen Detection |
| ELV872Mo01 | ELISA Kit for Synuclein Gamma (SNCg) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing."
Cancer Res. 57:759-764(1997) [PubMed] [Europe PMC] [Abstract]
"Organization, expression and polymorphism of the human persyn gene."
Hum. Mol. Genet. 7:1417-1424(1998) [PubMed] [Europe PMC] [Abstract]
"Identification, localization and characterization of the human gamma-synuclein gene."
Hum. Genet. 103:106-112(1998) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Synucleins are a novel class of substrates for G protein-coupled receptor kinases."
J. Biol. Chem. 275:26515-26522(2000) [PubMed] [Europe PMC] [Abstract]
"Gamma synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction."
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