Mucin 20 (MUC20)
Mucin 20, cell surface associated is a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Hu01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Hu01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Hu01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Hu01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Hu01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Mu01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Mu01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Mu01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Mu01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Mu01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Ra01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Ra01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Ra01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Ra01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Ra01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Ca01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Ca01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Ca01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Ca01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Ca01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Po01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Po01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Po01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Po01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Po01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Bo01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Bo01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Bo01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Bo01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Bo01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Rb01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Rb01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Rb01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Rb01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Rb01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV817Mo01 | Recombinant Mucin 20 (MUC20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV817Mo01 | Monoclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IP. |
| PAV817Mo01 | Polyclonal Antibody to Mucin 20 (MUC20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV817Mo01 | CLIA Kit for Mucin 20 (MUC20) | CLIA assay for Antigen Detection |
| ELV817Mo01 | ELISA Kit for Mucin 20 (MUC20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney."
J. Biol. Chem. 279:1968-1979(2004) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
"MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met."
Mol. Cell. Biol. 24:7456-7468(2004) [PubMed] [Europe PMC] [Abstract]
"Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy."
Am. J. Nephrol. 26:43-49(2006) [PubMed] [Europe PMC] [Abstract]
"Mucin gene expression in human male urogenital tract epithelia."
Hum. Reprod. 21:2783-2793(2006) [PubMed] [Europe PMC] [Abstract]