Glypican 4 (GPC4)
K-Glypican; Glypican Proteoglycan 4; Secreted glypican-4
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.The deduced 556-amino acid GPC4 protein is 93.5% identical to mouse K-glypican. Northern blot analysis detected 2 GPC4 transcripts of 2.9 kb and 4.3 kb in most human fetal and adult tissues tested.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Hu01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Hu01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Hu01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Hu01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Hu01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Mu01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Mu01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Mu01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Mu01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Mu01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Ra01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Ra01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Ra01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Ra01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Ra01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Ca01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Ca01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Ca01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Ca01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Ca01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Po01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Po01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Po01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Po01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Po01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Bo01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Bo01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Bo01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Bo01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Bo01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Rb01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Rb01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Rb01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Rb01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Rb01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV814Mo01 | Recombinant Glypican 4 (GPC4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV814Mo01 | Monoclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IP. |
| PAV814Mo01 | Polyclonal Antibody to Glypican 4 (GPC4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV814Mo01 | CLIA Kit for Glypican 4 (GPC4) | CLIA assay for Antigen Detection |
| ELV814Mo01 | ELISA Kit for Glypican 4 (GPC4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"GPC4, the gene for human K-glypican, flanks GPC3 on Xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome."
Genomics 53:1-11(1998) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss-of-function mutations in the GPC3 gene."
Hum. Mol. Genet. 9:1321-1328(2000) [PubMed] [Europe PMC] [Abstract]