Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7)
CD27; S152; T14; Tp55; CD27L receptor;
CD27 is a tumor necrosis factor receptor. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor.
CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Hu01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Hu01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Hu01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Hu01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Hu01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Mu01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Mu01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Mu01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Mu01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Mu01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Ra01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Ra01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Ra01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Ra01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Ra01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Ca01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Ca01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Ca01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Ca01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Ca01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Po01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Po01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Po01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Po01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Po01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Bo01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Bo01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Bo01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Bo01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Bo01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Rb01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Rb01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Rb01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Rb01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Rb01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV769Mo01 | Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV769Mo01 | Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IP. |
| PAV769Mo01 | Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV769Mo01 | CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | CLIA assay for Antigen Detection |
| ELV769Mo01 | ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family."
J. Immunol. 147:3165-3169(1991) [PubMed] [Europe PMC] [Abstract]
"Genomic organization and chromosomal localization of the human CD27 gene."
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"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
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"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
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"The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2."
Eur. J. Immunol. 28:2208-2216(1998) [PubMed] [Europe PMC] [Abstract]
"CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein."
Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351(1997) [PubMed] [Europe PMC] [Abstract]
"Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
"CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia."
J. Allergy Clin. Immunol. 129:787-793(2012) [PubMed] [Europe PMC] [Abstract]
"Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27."
Haematologica 98:473-478(2013) [PubMed] [Europe PMC] [Abstract]