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Protein Tyrosine Phosphatase Receptor Type K (PTPRK)

R-PTP-Kappa; PTPR-K; Protein-tyrosine phosphatase kappa

Receptor-type tyrosine-protein phosphatase kappa isa member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Hu01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Hu01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Hu01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Hu01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Mu01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Mu01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Mu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Mu01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Mu01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Ra01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Ra01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Ra01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Ra01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Ra01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Ca01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Ca01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Ca01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Ca01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Ca01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Po01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Po01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Po01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Po01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Po01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Bo01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Bo01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Bo01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Bo01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Bo01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Rb01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Rb01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Rb01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Rb01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Rb01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV765Mo01 Recombinant Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV765Mo01 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IP.
PAV765Mo01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type K (PTPRK) WB; IHC; ICC; IF.
Assay Kits CLV765Mo01 CLIA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) CLIA assay for Antigen Detection
ELV765Mo01 ELISA Kit for Protein Tyrosine Phosphatase Receptor Type K (PTPRK) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Association of human protein-tyrosine phosphatase kappa with members of the armadillo family."
J. Biol. Chem. 271:16712-16719(1996) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase."
Gene 186:77-82(1997) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis."
Curr. Biol. 19:1788-1798(2009) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Large-scale structural analysis of the classical human protein tyrosine phosphatome."
Cell 136:352-363(2009) [PubMed] [Europe PMC] [Abstract]