Chemokine C-C-Motif Ligand 16 (CCL16)
SCYA16; SCYL4; LEC; HCC4; LMC; LCC1; CKb12; Mtn1; CC-4; Monotactin-1; IL-10-inducible chemokine; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Liver-expressed chemokine (LEC)/CCL16 is a human CC chemokine selectively expressed in the liver.
Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. Its gene is located on chromosome 17, in humans, among a cluster of other CC chemokines. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Hu01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Hu01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Hu01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Hu01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Hu01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Mu01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Mu01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Mu01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Mu01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Mu01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Ra01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Ra01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Ra01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Ra01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Ra01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Ca01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Ca01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Ca01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Ca01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Ca01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Po01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Po01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Po01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Po01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Po01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Bo01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Bo01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Bo01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Bo01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Bo01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Rb01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Rb01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Rb01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Rb01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Rb01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV687Mo01 | Recombinant Chemokine C-C-Motif Ligand 16 (CCL16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV687Mo01 | Monoclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IP. |
| PAV687Mo01 | Polyclonal Antibody to Chemokine C-C-Motif Ligand 16 (CCL16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV687Mo01 | CLIA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | CLIA assay for Antigen Detection |
| ELV687Mo01 | ELISA Kit for Chemokine C-C-Motif Ligand 16 (CCL16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Characterization of a novel CC chemokine, HCC-4, whose expression is increased by interleukin-10."
Blood 91:4242-4247(1998) [PubMed] [Europe PMC] [Abstract]
"Isolation of cDNA encoding a novel human CC chemokine NCC-4/LEC."
Biochim. Biophys. Acta 1396:273-277(1998) [PubMed] [Europe PMC] [Abstract]
"Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES."
J. Interferon Cytokine Res. 19:227-234(1999) [PubMed] [Europe PMC] [Abstract]
"Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity."
Biochem. Biophys. Res. Commun. 247:217-222(1998) [PubMed] [Europe PMC] [Abstract]
"Genomic organization of the genes for human and mouse CC chemokine LEC."
DNA Cell Biol. 18:275-283(1999) [PubMed] [Europe PMC] [Abstract]
"Cloning, characterization and genomic organization of LCC-1 (scya16), a novel human CC chemokine expressed in liver."
Cytokine 12:101-109(2000) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]