Interleukin 19 (IL19)
MDA1; ZMDA1, IL-10C, NG.1; Melanoma Differentiation Associated Protein-Like Protein
Interleukin-19 is a cytokine that belongs to the IL-10 family of cytokines along with several other interleukins including IL-10, IL-20, IL-22, IL-24, IL-26, and several virus-encoded cytokines. It signals through the same cell surface receptor (IL-20R) that is used by IL-20 and IL-24. The IL-19 gene is expressed in resting monocytes and B cells. It is up-regulated in monocytes following stimulation with GM-CSF or lipopolysaccharide.
The predicted 177-amino acid protein contains a signal peptide, 2 potential N-linked glycosylation sites, and 4 conserved cysteine residues necessary for correct folding of the IL10 monomer. IL19 shares 82% identity with IL10 in the hydrophobic core, but only 53% similarity in the putative IL10 receptor-alpha (IL10RA)-interacting residues.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Hu01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Hu01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Hu01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Hu01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Hu01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Mu01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Mu01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Mu01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Mu01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Mu01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Ra01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Ra01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Ra01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Ra01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Ra01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Ca01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Ca01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Ca01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Ca01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Ca01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Po01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Po01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Po01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Po01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Po01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Bo01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Bo01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Bo01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Bo01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Bo01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Rb01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Rb01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Rb01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Rb01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Rb01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV634Mo01 | Recombinant Interleukin 19 (IL19) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV634Mo01 | Monoclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IP. |
| PAV634Mo01 | Polyclonal Antibody to Interleukin 19 (IL19) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV634Mo01 | CLIA Kit for Interleukin 19 (IL19) | CLIA assay for Antigen Detection |
| ELV634Mo01 | ELISA Kit for Interleukin 19 (IL19) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homolog of human interleukin-10 (IL-10)."
Genes Immun. 1:442-450(2000) [PubMed] [Europe PMC] [Abstract]
"IL-19 induces production of IL-6 and TNF-alpha and results in cell apoptosis through TNF-alpha."
J. Immunol. 169:4288-4297(2002) [PubMed] [Europe PMC] [Abstract]
"Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site."
BMC Genomics 10:518-518(2009) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of interleukin-19 defines a new subfamily of helical cytokines."
J. Biol. Chem. 278:3308-3313(2003) [PubMed] [Europe PMC] [Abstract]