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Nucleoporin 88kDa (NUP88)

Nuclear pore complex protein Nup88

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. 

NUP88 is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Fornerod et al. (1997) found that the NUP88 cDNA predicted a protein of 741 amino acids with a molecular mass of 85 kD. The protein migrated at 88 kD and was therefore named NUP88 to distinguish it from NUP85.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Hu01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Hu01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Hu01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Hu01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Hu01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Mu01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Mu01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Mu01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Mu01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Mu01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Ra01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Ra01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Ra01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Ra01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Ra01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Ca01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Ca01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Ca01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Ca01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Ca01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Po01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Po01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Po01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Po01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Po01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Bo01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Bo01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Bo01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Bo01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Bo01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Rb01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Rb01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Rb01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Rb01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Rb01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV626Mo01 Recombinant Nucleoporin 88kDa (NUP88) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV626Mo01 Monoclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IP.
PAV626Mo01 Polyclonal Antibody to Nucleoporin 88kDa (NUP88) WB; IHC; ICC; IF.
Assay Kits CLV626Mo01 CLIA Kit for Nucleoporin 88kDa (NUP88) CLIA assay for Antigen Detection
ELV626Mo01 ELISA Kit for Nucleoporin 88kDa (NUP88) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and the novel nuclear pore component Nup88."
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"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]