Contactin 4 (CNTN4)
AXCAM; BIG-2; CNTN4A; Brain-derived immunoglobulin superfamily protein 2
Contactin-4 is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
The gene is located on the short arm of chromosome 3 (3p26.3). It is a single copy gene within the Watson (plus) strand, 957,399 bases in length and encodes a protein of 1026 amino acids (molecular weight 113.454 kDa)Abnormal expression of this gene has been implicated in some cases of autism.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Hu01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Hu01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Hu01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Hu01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Hu01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Mu01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Mu01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Mu01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Mu01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Mu01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Ra01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Ra01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Ra01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Ra01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Ra01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Ca01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Ca01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Ca01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Ca01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Ca01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Po01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Po01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Po01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Po01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Po01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Bo01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Bo01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Bo01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Bo01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Bo01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Rb01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Rb01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Rb01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Rb01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Rb01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV614Mo01 | Recombinant Contactin 4 (CNTN4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV614Mo01 | Monoclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IP. |
| PAV614Mo01 | Polyclonal Antibody to Contactin 4 (CNTN4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV614Mo01 | CLIA Kit for Contactin 4 (CNTN4) | CLIA assay for Antigen Detection |
| ELV614Mo01 | ELISA Kit for Contactin 4 (CNTN4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel splice variant of the cell adhesion molecule contactin 4 (CNTN4) is mainly expressed in human brain."
J. Hum. Genet. 47:497-499(2002) [PubMed] [Europe PMC] [Abstract]
"Cloning and characterization of the human neural cell adhesion molecule, CNTN4 (alias BIG-2)."
Cytogenet. Genome Res. 101:17-23(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members."
Genomics 69:113-119(2000) [PubMed] [Europe PMC] [Abstract]
"Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome."
Am. J. Hum. Genet. 74:1286-1293(2004) [PubMed] [Europe PMC] [Abstract]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
"The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules."
Proc. Natl. Acad. Sci. U.S.A. 107:2443-2448(2010) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]