CD70 is a surface antigen found on activated, but not resting, The predicted 193-amino acid protein, has a 20-amino acid hydrophilic N-terminal domain that lacks a signal sequence; an 18-amino acid hydrophobic region that presumably functions as a transmembrane anchor; and a C-terminal domain that contains 2 potential N-linked glycosylation sites. Based on these features, the authors suggested that the C-terminal domain of CD27L is extracellular, and thus classified CD27L as a type II transmembrane protein.
CD27L is homologous to the ligands of the TNF receptor family, including TNF-alpha, TNF-beta, and the CD40 ligand, showing 19 to 24% amino acid sequence identity in the extracellular region.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Hu01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Hu01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Hu01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Hu01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Hu01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Mu01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Mu01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Mu01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Mu01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Mu01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Ra01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Ra01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Ra01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Ra01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Ra01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Ca01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Ca01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Ca01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Ca01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Ca01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Po01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Po01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Po01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Po01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Po01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Bo01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Bo01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Bo01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Bo01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Bo01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Rb01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Rb01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Rb01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Rb01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Rb01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV576Mo01
Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV576Mo01
Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IP.
PAV576Mo01
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
WB; IHC; ICC; IF.
Assay Kits
CLV576Mo01
CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
CLIA assay for Antigen Detection
ELV576Mo01
ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7)
Enzyme-linked immunosorbent assay for Antigen Detection
Reference
"Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor." Cell 73:447-456(1993) [PubMed] [Europe PMC] [Abstract]
"The cloning of CD70 and its identification as the ligand for CD27." J. Immunol. 152:1756-1761(1994) [PubMed] [Europe PMC] [Abstract]