Actin Beta (ACTb)
ACT-B; PS1TP5BP1; Actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed
Beta-actin (gene name ACTB) is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.
In a neoplastic cell line resulting from treatment of cultured human diploid fibroblasts with a chemical mutagen, Leavitt et al. (1982) observed a mutant form of beta actin. Toyama and Toyama (1984) isolated and characterized lines of KB cells resistant to cytochalasin B. They found that one resistant line had an alteration in beta-actin. Such cells bound less cytochalasin B than did parental KB cells. The authors suggested that the primary site of action of cytochalasin B on cell motility processes is beta-actin.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Hu01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Hu01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Hu01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Hu01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Hu01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Mu01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Mu01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Mu01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Mu01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Mu01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Ra01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Ra01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Ra01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Ra01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Ra01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Ca01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Ca01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Ca01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Ca01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Ca01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Po01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Po01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Po01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Po01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Po01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Bo01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Bo01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Bo01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Bo01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Bo01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Rb01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Rb01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Rb01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Rb01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Rb01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV493Mo01 | Recombinant Actin Beta (ACTb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV493Mo01 | Monoclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IP. |
| PAV493Mo01 | Polyclonal Antibody to Actin Beta (ACTb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV493Mo01 | CLIA Kit for Actin Beta (ACTb) | CLIA assay for Antigen Detection |
| ELV493Mo01 | ELISA Kit for Actin Beta (ACTb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA."
Nucleic Acids Res. 12:1687-1696(1984) [PubMed] [Europe PMC] [Abstract]
"Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns."
Proc. Natl. Acad. Sci. U.S.A. 82:6133-6137(1985) [PubMed] [Europe PMC] [Abstract]
"Direct proof that the primary site of action of cytochalasin on cell motility processes is actin."
J. Cell Biol. 116:933-941(1992) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]