Adenylate Cyclase 5 (ADCY5)
Adenylate cyclase type V; ATP pyrophosphate-lyase 5
Ludwig and Seuwen (2002) cloned full-length ADCY5. EST database analysis revealed 2 alternative polyadenylation sites. The deduced protein contains 1,261 amino acids. Semiquantitative RT-PCR detected high expression of ADCY5 in heart and testis, moderate expression in brain, prostate, ovary, small intestine, and colon, and low expression in lung and liver.
Gaudin et al. (1994) mapped the ADCY5 gene to chromosome 3. Using isotopic in situ hybridization, Haber et al. (1994) mapped the ADCY5 gene to 3q13.2-q21. By fluorescence in situ hybridization, Edelhoff et al. (1995) mapped the ADCY5 gene to human chromosome 3q13 and to mouse chromosome 16 in the B5 region. In both species, the gene maps close to GAP43 .
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Hu01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Hu01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Hu01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Hu01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Hu01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Mu01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Mu01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Mu01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Mu01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Mu01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Ra01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Ra01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Ra01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Ra01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Ra01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Ca01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Ca01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Ca01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Ca01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Ca01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Po01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Po01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Po01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Po01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Po01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Bo01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Bo01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Bo01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Bo01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Bo01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Rb01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Rb01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Rb01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Rb01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Rb01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV419Mo01 | Recombinant Adenylate Cyclase 5 (ADCY5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV419Mo01 | Monoclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IP. |
| PAV419Mo01 | Polyclonal Antibody to Adenylate Cyclase 5 (ADCY5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV419Mo01 | CLIA Kit for Adenylate Cyclase 5 (ADCY5) | CLIA assay for Antigen Detection |
| ELV419Mo01 | ELISA Kit for Adenylate Cyclase 5 (ADCY5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
"Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms."
J. Recept. Signal Transduct. 22:79-110(2002) [PubMed] [Europe PMC] [Abstract]
"Cloning and sequence of partial cDNAs encoding the human type V and VI adenylyl cyclases and subsequent RNA-quantification in various tissues."
Clin. Chim. Acta 285:155-161(1999) [PubMed] [Europe PMC] [Abstract]
"Raf kinase activation of adenylyl cyclases: isoform-selective regulation."
Mol. Pharmacol. 66:921-928(2004) [PubMed] [Europe PMC] [Abstract]
"Autosomal dominant familial dyskinesia and facial myokymia: single exome sequencing identifies a mutation in adenylyl cyclase 5."
Arch. Neurol. 69:630-635(2012) [PubMed] [Europe PMC] [Abstract]