Enolase, Muscle Specific (MSE)
ENO3; Beta Enolase; Enolase 3; 2-phospho-D-glycerate hydro-lyase; Skeletal muscle enolase
Beta-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene can be associated with metabolic myopathies that may result from decreased stability of the enzyme. Two transcripts have been identified for this gene that differ only in their 5' UTR.
Feo et al. (1990) mapped the muscle-specific beta-enolase (ENO3) to chromosome 17pter-p11 by analysis of rodent-human somatic cell hybrids and transfectant cell lines carrying different portions of chromosome 17. This muscle-specific enzyme maps to the region encoding the gene cluster for the sarcomeric myosin heavy chains (MYH1).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Hu01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Hu01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Hu01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Hu01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Hu01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Mu01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Mu01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Mu01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Mu01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Mu01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Ra01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Ra01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Ra01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Ra01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Ra01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Ca01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Ca01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Ca01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Ca01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Ca01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Po01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Po01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Po01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Po01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Po01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Bo01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Bo01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Bo01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Bo01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Bo01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Rb01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Rb01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Rb01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Rb01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Rb01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV401Mo01 | Recombinant Enolase, Muscle Specific (MSE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV401Mo01 | Monoclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IP. |
| PAV401Mo01 | Polyclonal Antibody to Enolase, Muscle Specific (MSE) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV401Mo01 | CLIA Kit for Enolase, Muscle Specific (MSE) | CLIA assay for Antigen Detection |
| ELV401Mo01 | ELISA Kit for Enolase, Muscle Specific (MSE) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Structure of human muscle (beta) enolase mRNA and protein deduced from a genomic clone."
Nucleic Acids Res. 17:8862-8862(1989) [PubMed] [Europe PMC] [Abstract]
"Nucleotide sequence of a cDNA encoding the human muscle-specific enolase (MSE)."
Nucleic Acids Res. 18:1893-1893(1990) [PubMed] [Europe PMC] [Abstract]
"Molecular structure of the human muscle-specific enolase gene (ENO3)."
Biochem. J. 275:427-433(1991) [PubMed] [Europe PMC] [Abstract]
"Structural features of the human gene for muscle-specific enolase. Differential splicing in the 5'-untranslated sequence generates two forms of mRNA."
Eur. J. Biochem. 214:367-374(1993) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Characterization of MR-1, a novel myofibrillogenesis regulator in human muscle."
Acta Biochim. Biophys. Sin. 36:412-418(2004) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Beta-enolase deficiency, a new metabolic myopathy of distal glycolysis."
Ann. Neurol. 50:202-207(2001) [PubMed] [Europe PMC] [Abstract]