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Azurocidin 1 (AZU1)

AZAMP; AZU; HBP; HUMAZUR; NAZC; CAP37; Cationic Antimicrobial Protein 37; Heparin-Binding Protein; Neutrophil Azurocidin

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator.

Azurocidin 1 is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Hu01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Hu01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Hu01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Hu01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Hu01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Mu01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Mu01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Mu01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Mu01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Mu01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Ra01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Ra01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Ra01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Ra01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Ra01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Ca01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Ca01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Ca01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Ca01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Ca01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Po01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Po01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Po01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Po01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Po01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Bo01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Bo01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Bo01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Bo01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Bo01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Rb01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Rb01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Rb01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Rb01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Rb01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV373Mo01 Recombinant Azurocidin 1 (AZU1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV373Mo01 Monoclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IP.
PAV373Mo01 Polyclonal Antibody to Azurocidin 1 (AZU1) WB; IHC; ICC; IF.
Assay Kits CLV373Mo01 CLIA Kit for Azurocidin 1 (AZU1) CLIA assay for Antigen Detection
ELV373Mo01 ELISA Kit for Azurocidin 1 (AZU1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"CAP 37, a 37 kD human neutrophil granule cationic protein shares homology with inflammatory proteinases."
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Proc. Natl. Acad. Sci. U.S.A. 86:5610-5614(1989) [PubMed] [Europe PMC] [Abstract]

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"Initial characterization of the human central proteome."
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"Structure of HBP, a multifunctional protein with a serine proteinase fold."
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"Atomic resolution structure of human HBP/CAP37/azurocidin."
Acta Crystallogr. D 54:598-609(1998) [PubMed] [Europe PMC] [Abstract]