Matrix Metalloproteinase 16 (MMP16)
MT3-MMP; MMP16; MMP-X2; MT-MMP2; MT-MMP3; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Hu01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Hu01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Hu01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Hu01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Hu01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Mu01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Mu01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Mu01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Mu01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Mu01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Ra01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Ra01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Ra01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Ra01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Ra01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Ca01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Ca01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Ca01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Ca01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Ca01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Po01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Po01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Po01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Po01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Po01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Bo01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Bo01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Bo01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Bo01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Bo01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Rb01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Rb01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Rb01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Rb01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Rb01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV301Mo01 | Recombinant Matrix Metalloproteinase 16 (MMP16) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV301Mo01 | Monoclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IP. |
| PAV301Mo01 | Polyclonal Antibody to Matrix Metalloproteinase 16 (MMP16) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV301Mo01 | CLIA Kit for Matrix Metalloproteinase 16 (MMP16) | CLIA assay for Antigen Detection |
| ELV301Mo01 | ELISA Kit for Matrix Metalloproteinase 16 (MMP16) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family."
J. Biol. Chem. 270:23013-23020(1995) [PubMed] [Europe PMC] [Abstract]
"Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA."
Biochim. Biophys. Acta 1354:159-170(1997) [PubMed] [Europe PMC] [Abstract]
"Expression of three membrane-type matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain."
J. Biol. Chem. 272:9749-9754(1997) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen."
J. Biol. Chem. 276:18786-18794(2001) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of the catalytic domain of MMP-16/MT3-MMP: characterization of MT-MMP specific features."
J. Mol. Biol. 336:213-225(2004) [PubMed] [Europe PMC] [Abstract]