Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1)
CD150; SLAMF1; CDw150; SLAM; Signaling lymphocytic activation molecule
Tatsuo et al. (2000) found that in MV-resistant cell lines infection with clinical MV and expression of SLAM, but not CD46, caused cytopathic effects (CPE). Likewise, anti-SLAM antibody protected cells from CPE when challenged with MV. Lymphoid cell lines expressing SLAM, but not lymphoid and myelomonocytic cell lines devoid of SLAM, were shown to be susceptible to MV. Tatsuo et al. (2000) noted that the expression of SLAM on activated B and T lymphocytes correlates with the pathology of MV infection in humans and monkeys, in which lymphoid organs are the chief sites of MV replication. They proposed that binding of MV to SLAM may impair the signaling functions of SLAM in lymphocyte activation and inhibit Th0/Th1 cytokine production, thereby promoting Th2 cytokine production.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Hu01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Hu01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Hu01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Hu01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Hu01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Mu01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Mu01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Mu01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Mu01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Mu01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Ra01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Ra01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Ra01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Ra01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Ra01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Ca01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Ca01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Ca01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Ca01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Ca01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Po01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Po01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Po01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Po01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Po01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Bo01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Bo01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Bo01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Bo01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Bo01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Rb01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Rb01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Rb01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Rb01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Rb01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV288Mo01 | Recombinant Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV288Mo01 | Monoclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IP. |
| PAV288Mo01 | Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV288Mo01 | CLIA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | CLIA assay for Antigen Detection |
| ELV288Mo01 | ELISA Kit for Signaling Lymphocytic Activation Molecule Family, Member 1 (SLAMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel receptor involved in T-cell activation."
Nature 376:260-263(1995) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Absence of SLAM mutations in EBV-associated lymphoproliferative disease patients."
J. Med. Virol. 70:131-136(2003) [PubMed] [Europe PMC] [Abstract]
"CDw150 associates with src-homology 2-containing inositol phosphatase and modulates CD95-mediated apoptosis."
J. Immunol. 162:5719-5727(1999) [PubMed] [Europe PMC] [Abstract]
"SLAM (CDw150) is a cellular receptor for measles virus."
Nature 406:893-897(2000) [PubMed] [Europe PMC] [Abstract]
"The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM."
Nature 395:462-469(1998) [PubMed] [Europe PMC] [Abstract]
"Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells."
EMBO J. 20:5840-5852(2001) [PubMed] [Europe PMC] [Abstract]
"A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome."
EMBO J. 21:314-323(2002) [PubMed] [Europe PMC] [Abstract]
"SAP couples Fyn to SLAM immune receptors."
Nat. Cell Biol. 5:155-160(2003) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]