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Octamer Binding Transcription Factor 1 (OCT1)

POU2F1; OTF1; NF-A1; POU Domain,Class 2,Transcription Factor 1; Octamer-binding transcription factor 1

POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Tomilin et al. (2000) found that the POU dimer from the OCT1 gene formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1, whereas POU dimers formed on the consensus MORE or on MOREs from immunoglobulin heavy chain promoters failed to interact. An interaction with OBF1 was precluded since the same OCT1 residues that form the MORE dimerization interface are also used for OBF1/OCT1 interactions on the PORE.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Hu01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Hu01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Hu01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Hu01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Hu01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Mu01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Mu01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Mu01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Mu01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Mu01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Ra01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Ra01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Ra01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Ra01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Ra01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Ca01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Ca01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Ca01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Ca01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Ca01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Po01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Po01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Po01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Po01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Po01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Bo01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Bo01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Bo01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Bo01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Bo01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Rb01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Rb01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Rb01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Rb01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Rb01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV281Mo01 Recombinant Octamer Binding Transcription Factor 1 (OCT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV281Mo01 Monoclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IP.
PAV281Mo01 Polyclonal Antibody to Octamer Binding Transcription Factor 1 (OCT1) WB; IHC; ICC; IF.
Assay Kits CLV281Mo01 CLIA Kit for Octamer Binding Transcription Factor 1 (OCT1) CLIA assay for Antigen Detection
ELV281Mo01 ELISA Kit for Octamer Binding Transcription Factor 1 (OCT1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain."
Cell 73:193-205(1993) [PubMed] [Europe PMC] [Abstract]

"Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics."
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