Cytochrome P450 21B (CYP21B)
CYP21A2; CPS1; CA21H; CAH1; CYP21; CYP21-B; 21-OHase; Steroid 21-hydroxylase; Cytochrome P450,Family 21,Subfamily A,Polypeptide 2
Steroid 21-hydroxylase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone.A defect within the CYP21B gene causes a disturbance of the development of the enzyme, which leads to congenital adrenal hyperplasia due to 21-hydroxylase deficiency. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought account for many cases of steroid 21-hydroxylase deficiency.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Hu01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Hu01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Hu01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Hu01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Hu01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Mu01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Mu01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Mu01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Mu01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Mu01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Ra01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Ra01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Ra01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Ra01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Ra01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Ca01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Ca01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Ca01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Ca01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Ca01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Po01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Po01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Po01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Po01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Po01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Bo01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Bo01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Bo01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Bo01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Bo01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Rb01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Rb01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Rb01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Rb01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Rb01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV276Mo01 | Recombinant Cytochrome P450 21B (CYP21B) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV276Mo01 | Monoclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IP. |
PAV276Mo01 | Polyclonal Antibody to Cytochrome P450 21B (CYP21B) | WB; IHC; ICC; IF. | |
Assay Kits | CLV276Mo01 | CLIA Kit for Cytochrome P450 21B (CYP21B) | CLIA assay for Antigen Detection |
ELV276Mo01 | ELISA Kit for Cytochrome P450 21B (CYP21B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Erratum
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