Receptor I For The Fc Region Of Immunoglobulin E (FceRI)
FCER1A; FCE1A; FcER1 High affinity immunoglobulin epsilon receptor subunit alpha
The high-affinity receptor Fc epsilon RI is a member of the immunoglobulin superfamily (it has two Ig-like domains). FcεRI is found on epidermal Langerhans cells, eosinophils, mast cells and basophils. As a result of its cellular distribution, this receptor plays a major role in controlling allergic responses.
FcεRI is also expressed on antigen-presenting cells, and controls the production of important immune mediators called cytokines that promote inflammation. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Hu01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Hu01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Hu01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Hu01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Hu01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Mu01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Mu01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Mu01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Mu01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Mu01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Ra01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Ra01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Ra01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Ra01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Ra01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Ca01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Ca01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Ca01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Ca01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Ca01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Po01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Po01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Po01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Po01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Po01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Bo01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Bo01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Bo01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Bo01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Bo01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Rb01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Rb01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Rb01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Rb01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Rb01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV254Mo01 | Recombinant Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV254Mo01 | Monoclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IP. |
| PAV254Mo01 | Polyclonal Antibody to Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV254Mo01 | CLIA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | CLIA assay for Antigen Detection |
| ELV254Mo01 | ELISA Kit for Receptor I For The Fc Region Of Immunoglobulin E (FceRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor."
Nucleic Acids Res. 16:3584-3584(1988) [PubMed] [Europe PMC] [Abstract]
"Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products."
Proc. Natl. Acad. Sci. U.S.A. 85:1907-1911(1988) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"High-level expression of the truncated alpha chain of human high-affinity receptor for IgE as a soluble form by baculovirus-infected insect cells. Biochemical characterization of the recombinant product."
Eur. J. Biochem. 220:593-598(1994) [PubMed] [Europe PMC] [Abstract]
"A modeling study of the alpha-subunit of human high-affinity receptor for immunoglobulin-E."
Receptor 2:129-144(1992) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of the human high-affinity IgE receptor."
Cell 95:951-961(1998) [PubMed] [Europe PMC] [Abstract]
"The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms."
J. Mol. Biol. 311:1049-1062(2001) [PubMed] [Europe PMC] [Abstract]