Macrophage Scavenger Receptor 1 (MSR1)
CD204; MSR1; SCARA1; SR-A; PhSR1; PhSR2; Macrophage acetylated LDL receptor I and II; Scavenger receptor class A member 1
Macrophage scavenger receptor 1, also known as MSR1, is a protein which in humans is encoded by the MSR1 gene.MSR1 has also recently been designated CD204. This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene.
These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Hu01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Hu01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Hu01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Hu01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Hu01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Mu01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Mu01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Mu01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Mu01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Mu01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Ra01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Ra01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Ra01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Ra01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Ra01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Ca01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Ca01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Ca01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Ca01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Ca01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Po01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Po01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Po01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Po01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Po01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Bo01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Bo01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Bo01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Bo01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Bo01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Rb01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Rb01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Rb01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Rb01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Rb01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV244Mo01 | Recombinant Macrophage Scavenger Receptor 1 (MSR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV244Mo01 | Monoclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IP. |
| PAV244Mo01 | Polyclonal Antibody to Macrophage Scavenger Receptor 1 (MSR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV244Mo01 | CLIA Kit for Macrophage Scavenger Receptor 1 (MSR1) | CLIA assay for Antigen Detection |
| ELV244Mo01 | ELISA Kit for Macrophage Scavenger Receptor 1 (MSR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Proc. Natl. Acad. Sci. U.S.A. 87:9133-9137(1990) [PubMed] [Europe PMC] [Abstract]
"A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake."
J. Lipid Res. 39:531-543(1998) [PubMed] [Europe PMC] [Abstract]
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Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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J. Biol. Chem. 268:2120-2125(1993) [PubMed] [Europe PMC] [Abstract]
"Structures of class A macrophage scavenger receptors. Electron microscopic study of flexible, multidomain, fibrous proteins and determination of the disulfide bond pattern of the scavenger receptor cysteine-rich domain."
J. Biol. Chem. 271:26924-26930(1996) [PubMed] [Europe PMC] [Abstract]
"Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk."
Nat. Genet. 32:321-325(2002) [PubMed] [Europe PMC] [Abstract]
"An unappreciated role for RNA surveillance."
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J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
"Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma."
JAMA 306:410-419(2011) [PubMed] [Europe PMC] [Abstract]