Cluster Of Differentiation 164 (CD164)
MGC-24v; Endolyn; CD164 Molecule,Sialomucin; Sialomucin core protein 24; Multi-glycosylated core protein 24
CD164 is a transmembrane isoform of the mucin-like glycoprotein MGC-24. MGC-24 is a 24 kDa protein rich in hydroxyl amino acids and cysteine, and lack repeating motifs identified originally in human gastric carcinoma cells as a protein binding peanut agglutinin. High levels of MGC-24 mRNA are expressed in normal tissues of the colon, small intestine and thyroid, and in some nude mouse-transplanted colorectal and pancreatic adenocarcinomas.
Kurosawa et al (1999) have reported that in the mouse only the transmembrane form is expressed in many organs. CD164 is expressed by human CD34(+) hematopoietic progenitor cells. The subpopulations of CD34(+) cells expressing CD164 include the majority of CFU-GM, BFU-E, and hierarchically more primitive precursors (pre-CFU). .
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Hu01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Hu01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Hu01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Hu01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Hu01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Mu01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Mu01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Mu01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Mu01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Mu01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Ra01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Ra01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Ra01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Ra01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Ra01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Ca01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Ca01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Ca01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Ca01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Ca01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Po01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Po01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Po01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Po01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Po01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Bo01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Bo01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Bo01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Bo01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Bo01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Rb01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Rb01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Rb01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Rb01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Rb01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV241Mo01 | Recombinant Cluster Of Differentiation 164 (CD164) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV241Mo01 | Monoclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IP. |
| PAV241Mo01 | Polyclonal Antibody to Cluster Of Differentiation 164 (CD164) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV241Mo01 | CLIA Kit for Cluster Of Differentiation 164 (CD164) | CLIA assay for Antigen Detection |
| ELV241Mo01 | ELISA Kit for Cluster Of Differentiation 164 (CD164) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric carcinoma cells: sequence analysis and examination of gene expression."
J. Biochem. 112:609-615(1992) [PubMed] [Europe PMC] [Abstract]
"The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis."
Blood 92:2613-2628(1998) [PubMed] [Europe PMC] [Abstract]
"CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor."
J. Immunol. 165:840-851(2000) [PubMed] [Europe PMC] [Abstract]
"Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn."
J. Biol. Chem. 276:2139-2152(2001) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis."
BMC Cancer 6:195-195(2006) [PubMed] [Europe PMC] [Abstract]
"Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells."
Blood 109:1825-1833(2007) [PubMed] [Europe PMC] [Abstract]