Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1)
PLC-B1; PI-PLC; PLC-154; PLC-I; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta-1; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I
Phospholipase C-beta (PLCB) catalyzes the generation of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) from phosphatidylinositol 4,5-bisphosphate (IP2), a key step in the intracellular transduction of many extracellular signals. PLCB1 is one of several mammalian PLCB isoforms which differ in their function and expression patterns in vivo.
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Hu01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Hu01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Hu01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Hu01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Hu01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Mu01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Mu01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Mu01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Mu01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Mu01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Ra01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Ra01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Ra01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Ra01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Ra01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Ca01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Ca01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Ca01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Ca01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Ca01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Po01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Po01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Po01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Po01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Po01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Bo01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Bo01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Bo01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Bo01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Bo01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Rb01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Rb01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Rb01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Rb01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Rb01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV239Mo01 | Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV239Mo01 | Monoclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IP. |
| PAV239Mo01 | Polyclonal Antibody to Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV239Mo01 | CLIA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | CLIA assay for Antigen Detection |
| ELV239Mo01 | ELISA Kit for Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"Identification and chromosomal localisation by fluorescence in situ hybridisation of human gene of phosphoinositide-specific phospholipase C beta 1."
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Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]