GDP Dissociation Inhibitor 1 (GDI1)
GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; Guanine Nucleotide Dissociation Inhibitor; Rab GDP Dissociation Inhibitor Alpha 1; Oligophrenin-2
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs.
GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.Rab GTPases cycles between the cytosolic compartment, where it is bound to a protein called GDI (GDP Dissociation Inhibitor), and the membrane, where it interacts with a receptor, a nucleotide exchange factor, a GAP (GTPase Activating Protein) and probably other factors that link it to the appropriate SNARE.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Hu01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Hu01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Hu01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Hu01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Hu01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Mu01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Mu01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Mu01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Mu01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Mu01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Ra01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Ra01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Ra01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Ra01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Ra01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Ca01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Ca01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Ca01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Ca01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Ca01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Po01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Po01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Po01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Po01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Po01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Bo01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Bo01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Bo01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Bo01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Bo01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Rb01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Rb01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Rb01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Rb01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Rb01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV218Mo01 | Recombinant GDP Dissociation Inhibitor 1 (GDI1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV218Mo01 | Monoclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IP. |
| PAV218Mo01 | Polyclonal Antibody to GDP Dissociation Inhibitor 1 (GDI1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV218Mo01 | CLIA Kit for GDP Dissociation Inhibitor 1 (GDI1) | CLIA assay for Antigen Detection |
| ELV218Mo01 | ELISA Kit for GDP Dissociation Inhibitor 1 (GDI1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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, Submitted (MAR-2007) to UniProtKB
"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
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"GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation."
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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Nat. Genet. 19:134-139(1998) [PubMed] [Europe PMC] [Abstract]
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Hum. Mol. Genet. 7:1311-1315(1998) [PubMed] [Europe PMC] [Abstract]