Interleukin 17 Receptor A (IL17RA)
CDw217; CD217; IL17R-A; IL17-RA; IL17R-A; IL17R; HIL-17R
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL17 induces nuclear factor kappa-B (NFKB) and the expression of IL6, intercellular adhesion molecule-1 (ICAM1), granulocyte macrophage colony-stimulating factor, and prostaglandin E2, as well as the maturation of CD34-positive hematopoietic precursors into neutrophils. IL17R is a receptor for IL17.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Hu01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Hu01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Hu01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Hu01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Hu01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Mu01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Mu01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Mu01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Mu01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Mu01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Ra01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Ra01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Ra01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Ra01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Ra01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Ca01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Ca01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Ca01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Ca01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Ca01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Po01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Po01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Po01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Po01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Po01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Bo01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Bo01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Bo01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Bo01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Bo01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Rb01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Rb01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Rb01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Rb01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Rb01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV194Mo01 | Recombinant Interleukin 17 Receptor A (IL17RA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV194Mo01 | Monoclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IP. |
| PAV194Mo01 | Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV194Mo01 | CLIA Kit for Interleukin 17 Receptor A (IL17RA) | CLIA assay for Antigen Detection |
| ELV194Mo01 | ELISA Kit for Interleukin 17 Receptor A (IL17RA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Science 332:65-68(2011) [PubMed] [Europe PMC] [Abstract]
"Identification of a soluble isoform of human IL-17RA generated by alternative splicing."
Cytokine 64:642-645(2013) [PubMed] [Europe PMC] [Abstract]
"Structural basis of receptor sharing by interleukin 17 cytokines."
Nat. Immunol. 10:1245-1251(2009) [PubMed] [Europe PMC] [Abstract]