Phosphoglycerate Mutase 2, Muscle (PGAM2)
PGAM-M; BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M
The function of PGAM2 : Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. It can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.In mammals, the enzyme subunits appear to be either a muscle-derived form (m-type) or other tissue (b-type for brain where the b-isozyme was originally isolated). Existing as a dimer, the enzyme then has 3 isozymes depending on which subunit forms makeup the whole molecule (mm, bb or mb). The mm-type is found mainly in smooth muscle almost exclusively. The mb-isozyme is found in cardiac and skeletal muscle and the bb-type is found in the rest of tissues. While all three isozymes may be found in any tissue, the above distributions are based on prevalence in each.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Hu01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Hu01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Hu01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Hu01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Hu01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Mu01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Mu01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Mu01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Mu01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Mu01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Ra01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Ra01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Ra01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Ra01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Ra01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Ca01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Ca01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Ca01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Ca01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Ca01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Po01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Po01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Po01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Po01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Po01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Bo01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Bo01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Bo01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Bo01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Bo01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Rb01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Rb01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Rb01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Rb01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Rb01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV193Mo01 | Recombinant Phosphoglycerate Mutase 2, Muscle (PGAM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV193Mo01 | Monoclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IP. |
| PAV193Mo01 | Polyclonal Antibody to Phosphoglycerate Mutase 2, Muscle (PGAM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV193Mo01 | CLIA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | CLIA assay for Antigen Detection |
| ELV193Mo01 | ELISA Kit for Phosphoglycerate Mutase 2, Muscle (PGAM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation and characterization of the gene encoding the muscle-specific isozyme of human phosphoglycerate mutase."
Gene 91:225-232(1990) [PubMed] [Europe PMC] [Abstract]
"Structure of the gene encoding the muscle-specific subunit of human phosphoglycerate mutase."
J. Biol. Chem. 264:15334-15337(1989) [PubMed] [Europe PMC] [Abstract]
"Isolation of a cDNA encoding the muscle-specific subunit of human phosphoglycerate mutase."
J. Biol. Chem. 262:14612-14617(1987) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."
Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
"The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency."
Am. J. Hum. Genet. 52:472-477(1993) [PubMed] [Europe PMC] [Abstract]
"Manifesting heterozygotes in a Japanese family with a novel mutation in the muscle-specific phosphoglycerate mutase (PGAM-M) gene."
Neuromuscul. Disord. 9:399-402(1999) [PubMed] [Europe PMC] [Abstract]