Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1)
N-AChRB1; NAChRB1; CMS2A; SCCMS; ACHRB; CHRNB; CMS1D; N-AChR-B1; Neuronal Acetylcholine Receptor Beta 1; Acetylcholine receptor subunit beta
Acetylcholine receptor subunit beta is a protein encoded by the CHRNB1 gene.The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor.
The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Hu01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Hu01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Hu01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Hu01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Hu01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Mu01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Mu01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Mu01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Mu01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Mu01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Ra01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Ra01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Ra01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Ra01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Ra01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Ca01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Ca01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Ca01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Ca01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Ca01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Po01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Po01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Po01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Po01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Po01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Bo01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Bo01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Bo01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Bo01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Bo01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Rb01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Rb01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Rb01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Rb01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Rb01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV190Mo01 | Recombinant Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV190Mo01 | Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IP. |
| PAV190Mo01 | Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV190Mo01 | CLIA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | CLIA assay for Antigen Detection |
| ELV190Mo01 | ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Nucleotide sequence of human muscle acetylcholine receptor beta-subunit."
Nucleic Acids Res. 17:4391-4391(1989) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome."
Ann. Neurol. 39:712-723(1996) [PubMed] [Europe PMC] [Abstract]
"New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome."
Hum. Mol. Genet. 5:1217-1227(1996) [PubMed] [Europe PMC] [Abstract]
"Mutation causing congenital myasthenia reveals acetylcholine receptor beta/delta subunit interaction essential for assembly."
J. Clin. Invest. 104:1403-1410(1999) [PubMed] [Europe PMC] [Abstract]