Carnitine Acylcarnitine Translocase (CACT)
SLC25A20; CAC; Solute Carrier Family 25 Member 20; Carnitine Acylcarnitine Carrier; Mitochondrial carnitine/acylcarnitine carrier protein
Carnitine-acylcarnitine translocase is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Hu01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Hu01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Hu01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Hu01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Hu01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Mu01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Mu01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Mu01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Mu01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Mu01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Ra01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Ra01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Ra01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Ra01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Ra01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Ca01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Ca01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Ca01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Ca01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Ca01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Po01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Po01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Po01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Po01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Po01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Bo01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Bo01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Bo01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Bo01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Bo01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Rb01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Rb01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Rb01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Rb01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Rb01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV181Mo01 | Recombinant Carnitine Acylcarnitine Translocase (CACT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV181Mo01 | Monoclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IP. |
| PAV181Mo01 | Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV181Mo01 | CLIA Kit for Carnitine Acylcarnitine Translocase (CACT) | CLIA assay for Antigen Detection |
| ELV181Mo01 | ELISA Kit for Carnitine Acylcarnitine Translocase (CACT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient."
Am. J. Hum. Genet. 61:1239-1245(1997) [PubMed] [Europe PMC] [Abstract]
"The structure and organization of the human carnitine/acylcarnitine translocase (CACT) gene."
Biochem. Biophys. Res. Commun. 252:770-774(1998) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"A novel molecular defect of the carnitine acylcarnitine translocase gene in a Saudi patient."
Clin. Genet. 64:163-165(2003) [PubMed] [Europe PMC] [Abstract]
"Response to therapy in carnitine/acylcarnitine translocase (CACT) deficiency due to a novel missense mutation."
Am. J. Med. Genet. A 126:150-155(2004) [PubMed] [Europe PMC] [Abstract]
"Molecular and functional analysis of SLC25A20 mutations causing carnitine-acylcarnitine translocase deficiency."
Hum. Mutat. 24:312-320(2004) [PubMed] [Europe PMC] [Abstract]