Angiotensin II Receptor 1 (AGTR1)
AT1R; AG2S; AG2-S; AGTR1A; AGTR1B; AT1; AT1B; AT2R1; AT2-R1; AT2R1A; AT2R1B; HAT1R; AT1 Receptor; Angiotensin Receptor 1B
Angiotensin II receptor, type 1 or AT1 receptor is an angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system.It is the best elucidated angiotensin receptor.
The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to Gq/11 and thus activates phospholipase C and increases the cytosolic Ca2+ concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. Activated receptor also inhibits adenylate cyclase and activates various tyrosine kinases.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Hu01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Hu01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Hu01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Hu01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Hu01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Mu01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Mu01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Mu01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Mu01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Mu01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Ra01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Ra01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Ra01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Ra01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Ra01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Ca01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Ca01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Ca01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Ca01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Ca01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Po01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Po01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Po01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Po01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Po01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Bo01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Bo01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Bo01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Bo01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Bo01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Rb01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Rb01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Rb01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Rb01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Rb01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV180Mo01 | Recombinant Angiotensin II Receptor 1 (AGTR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV180Mo01 | Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IP. |
| PAV180Mo01 | Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV180Mo01 | CLIA Kit for Angiotensin II Receptor 1 (AGTR1) | CLIA assay for Antigen Detection |
| ELV180Mo01 | ELISA Kit for Angiotensin II Receptor 1 (AGTR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning, expression, and characterization of a gene encoding the human angiotensin II type 1A receptor."
Biochem. Biophys. Res. Commun. 186:277-284(1992) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor."
Biochem. Biophys. Res. Commun. 183:8-13(1992) [PubMed] [Europe PMC] [Abstract]
"Cloning and characterization of a human angiotensin II type 1 receptor."
Biochem. Biophys. Res. Commun. 183:989-995(1992) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor."
Biochem. Biophys. Res. Commun. 183:910-916(1992) [PubMed] [Europe PMC] [Abstract]
"Genetic analysis of the human type-1 angiotensin II receptor."
Mol. Endocrinol. 6:1113-1118(1992) [PubMed] [Europe PMC] [Abstract]
"Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression."
Biochem. Biophys. Res. Commun. 199:467-474(1994) [PubMed] [Europe PMC] [Abstract]
"Type 1 angiotensin II receptors of adrenal tumors."
Steroids 60:28-34(1995) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor."
Circulation 111:1806-1813(2005) [PubMed] [Europe PMC] [Abstract]
"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
"Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."
Nat. Genet. 37:964-968(2005) [PubMed] [Europe PMC] [Abstract]