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Citrate Synthase (CS)

Citrate (Si)-synthase, mitochondrial

The enzyme citrate synthase (E.C. 2.3.3.1) exists in nearly all living cells and stands as a pace-making enzyme in the first step of the Citric Acid Cycle (or Krebs Cycle). Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix, but is encoded by nuclear DNA rather than mitochondrial. It is synthesized using cytoplasmic ribosomes, then transported into the mitochondrial matrix. Citrate synthase is commonly used as a quantitative enzyme marker for the presence of intact mitochondria. Citrate synthase catalyzes the condensation reaction of the two-carbon acetate residue from acetyl coenzyme A and a molecule of four-carbon oxaloacetate to form the six-carbon citrate. Oxaloacetate will be regenerated after the completion of one round of the Krebs Cycle.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Hu01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Hu01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Hu01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Hu01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Hu01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Mu01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Mu01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Mu01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Mu01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Mu01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Ra01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Ra01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Ra01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Ra01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Ra01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Ca01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Ca01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Ca01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Ca01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Ca01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Po01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Po01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Po01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Po01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Po01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Bo01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Bo01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Bo01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Bo01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Bo01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Rb01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Rb01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Rb01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Rb01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Rb01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV177Mo01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV177Mo01 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAV177Mo01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IF.
Assay Kits CLV177Mo01 CLIA Kit for Citrate Synthase (CS) CLIA assay for Antigen Detection
ELV177Mo01 ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning and molecular analysis of the human citrate synthase gene."
Genome 41:733-738(1998) [PubMed] [Europe PMC] [Abstract]

"Cloning and tissue expression pattern analysis of the human citrate synthase cDNA."
Shi Yan Sheng Wu Xue Bao 33:207-214(2000) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
Biochem. J. 383:237-248(2004) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]