Fatty Acid Binding Protein 4, Adipocyte (FABP4)
A-FABP; AFABP; AP2; Adipocyte Protein 2; Adipocyte-type fatty acid-binding protein
aP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4). Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease,diabetes, asthma, obesity, and fatty liver disease.
Baxa et al. (1989) purified human adipocyte FABP (called H-ALBP by them) from normal subcutaneous adipose tissue. The 15-kD protein composed about 1% of total cytosolic protein in human adipose tissue. They also cloned a full-length cDNA that encodes a predicted 132-amino acid polypeptide. Baxa et al. (1989) also identified a consensus tyrosyl kinase phosphorylation site.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Hu01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Hu01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Hu01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Hu01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Hu01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Mu01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Mu01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Mu01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Mu01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Mu01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Ra01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Ra01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Ra01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Ra01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Ra01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Ca01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Ca01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Ca01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Ca01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Ca01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Po01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Po01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Po01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Po01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Po01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Bo01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Bo01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Bo01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Bo01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Bo01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Rb01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Rb01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Rb01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Rb01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Rb01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV146Mo01 | Recombinant Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV146Mo01 | Monoclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IP. |
| PAV146Mo01 | Polyclonal Antibody to Fatty Acid Binding Protein 4, Adipocyte (FABP4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV146Mo01 | CLIA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | CLIA assay for Antigen Detection |
| ELV146Mo01 | ELISA Kit for Fatty Acid Binding Protein 4, Adipocyte (FABP4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA."
Biochemistry 28:8683-8690(1989) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Resveratrol-induced changes of the human adipocyte secretion profile."
J. Proteome Res. 11:4733-4743(2012) [PubMed] [Europe PMC] [Abstract]
"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target."
Bioorg. Med. Chem. Lett. 14:4445-4448(2004) [PubMed] [Europe PMC] [Abstract]
"Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)."
Acta Crystallogr. F 62:1058-1060(2006) [PubMed] [Europe PMC] [Abstract]