Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
CD256; APRIL; TALL2; TRDL1; ZTNF2; A Proliferation Inducing Ligand; TNF And APOL Related Leukocyte Expressed Ligand 2; TNF-Related Death Ligand 1
Tumor necrosis factor ligand superfamily member 13 is a member of the tumor necrosis factor (TNF) ligand family. Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Hu01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Hu01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Hu01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Hu01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Hu01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Mu01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Mu01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Mu01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Mu01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Mu01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Ra01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Ra01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Ra01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Ra01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Ra01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Ca01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Ca01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Ca01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Ca01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Ca01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Po01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Po01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Po01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Po01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Po01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Bo01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Bo01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Bo01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Bo01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Bo01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Rb01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Rb01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Rb01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Rb01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Rb01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV089Mo01 | Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV089Mo01 | Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IP. |
| PAV089Mo01 | Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV089Mo01 | CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | CLIA assay for Antigen Detection |
| ELV089Mo01 | ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth."
J. Exp. Med. 188:1185-1190(1998) [PubMed] [Europe PMC] [Abstract]
"TALL-1 is a novel member of the TNF family that is down-regulated by mitogens."
J. Leukoc. Biol. 65:680-683(1999) [PubMed] [Europe PMC] [Abstract]
"APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death."
Cancer Res. 60:1021-1027(2000) [PubMed] [Europe PMC] [Abstract]
"An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein."
EMBO J. 21:5711-5720(2002) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
Nat. Immunol. 1:252-256(2000) [PubMed] [Europe PMC] [Abstract]
"Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase."
EMBO Rep. 2:945-951(2001) [PubMed] [Europe PMC] [Abstract]