Oncostatin M Receptor (OSMR)
OSMRB; IL-31RB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta
Oncostatin M receptor is a receptor for oncostatin M.Oncostatin M (OSM) is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 (IL6ST) as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with leukemia inhibitory factor receptor (LIFR), induces a proliferative response in permissive cells. Mosley et al. (1996) used degenerate PCR to clone a novel hematopoietin receptor which they called the oncostatin M-specific receptor beta subunit (OSMR-beta). Sequencing revealed that this gene encodes a 979-amino acid protein containing characteristic motifs of the hematopoietin receptor family.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Hu01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Hu01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Hu01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Hu01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Hu01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Mu01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Mu01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Mu01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Mu01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Mu01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Ra01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Ra01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Ra01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Ra01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Ra01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Ca01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Ca01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Ca01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Ca01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Ca01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Po01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Po01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Po01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Po01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Po01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Bo01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Bo01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Bo01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Bo01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Bo01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Rb01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Rb01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Rb01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Rb01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Rb01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV078Mo01 | Recombinant Oncostatin M Receptor (OSMR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV078Mo01 | Monoclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IP. |
| PAV078Mo01 | Polyclonal Antibody to Oncostatin M Receptor (OSMR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV078Mo01 | CLIA Kit for Oncostatin M Receptor (OSMR) | CLIA assay for Antigen Detection |
| ELV078Mo01 | ELISA Kit for Oncostatin M Receptor (OSMR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation."
J. Biol. Chem. 271:32635-32643(1996) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice."
Nat. Immunol. 5:752-760(2004) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis."
Am. J. Hum. Genet. 82:73-80(2008) [PubMed] [Europe PMC] [Abstract]
"Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis."
Eur. J. Hum. Genet. 18:26-32(2010) [PubMed] [Europe PMC] [Abstract]