Inhibin Beta B (INHbB)
INH-BB; Activin AB Beta Polypeptide
Inhibin, beta B is a protein which in humans is encoded by the INHBB gene.INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.Inhibins are heterodimeric glycoproteins composed of an alpha subunit (INHA) and one of two homologous, but distinct, beta; subunits (beta A or beta B, this protein).
mRNA for the two subunits has been demonstrated in the testes of adult rats.Inhibin can bind specifically to testicular interstitial cells throughout development and may be an important regulator of Leydig cell testosterone production or interstitial cell function.The inhibin beta B subunit joins the alpha; subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Hu01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Hu01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Hu01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Hu01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Hu01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Mu01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Mu01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Mu01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Mu01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Mu01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Ra01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Ra01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Ra01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Ra01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Ra01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Ca01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Ca01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Ca01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Ca01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Ca01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Po01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Po01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Po01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Po01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Po01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Bo01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Bo01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Bo01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Bo01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Bo01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Rb01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Rb01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Rb01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Rb01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Rb01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV077Mo01 | Recombinant Inhibin Beta B (INHbB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV077Mo01 | Monoclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IP. |
| PAV077Mo01 | Polyclonal Antibody to Inhibin Beta B (INHbB) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV077Mo01 | CLIA Kit for Inhibin Beta B (INHbB) | CLIA assay for Antigen Detection |
| ELV077Mo01 | ELISA Kit for Inhibin Beta B (INHbB) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Activin B: precursor sequences, genomic structure and in vitro activities."
Mol. Endocrinol. 3:1352-1358(1989) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Characterization and regulation of testicular inhibin beta-subunit mRNA."
Mol. Endocrinol. 3:939-948(1989) [PubMed] [Europe PMC] [Abstract]
"Structure of two human ovarian inhibins."
Biochem. Biophys. Res. Commun. 135:957-964(1986) [PubMed] [Europe PMC] [Abstract]
"Purification and characterization of recombinant human activin B."
Biochim. Biophys. Acta 1039:135-141(1990) [PubMed] [Europe PMC] [Abstract]
"Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG)."
Endocrinology 144:1671-1674(2003) [PubMed] [Europe PMC] [Abstract]