Cluster Of Differentiation 7 (CD7)
GP40; LEU9; TP41; Tp40; p41 Protein; T-cell Antigen CD7; T-cell Leukemia Antigen; T-cell surface antigen Leu-9
CD7 is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
The CD7 antigen is a cell surface glycoprotein found on thymocytes and mature T cells. It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage and the most reliable clinical marker of T-cell acute lymphocytic leukemia. Aruffo and Seed (1987) isolated and sequenced a full-length CD7 cDNA as well as a cDNA for an unusual intron-bearing precursor. They found that COS cells expressing CD7 do not bind IgM. Schanberg et al. (1991) isolated and characterized the human CD7 gene and its 5-prime flanking region; the gene comprises 4 exons that span 3.5 kb.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Hu01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Hu01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Hu01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Hu01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Hu01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Mu01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Mu01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Mu01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Mu01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Mu01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Ra01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Ra01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Ra01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Ra01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Ra01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Ca01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Ca01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Ca01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Ca01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Ca01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Po01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Po01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Po01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Po01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Po01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Bo01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Bo01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Bo01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Bo01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Bo01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Rb01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Rb01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Rb01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Rb01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Rb01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV056Mo01 | Recombinant Cluster Of Differentiation 7 (CD7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV056Mo01 | Monoclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IP. |
| PAV056Mo01 | Polyclonal Antibody to Cluster Of Differentiation 7 (CD7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV056Mo01 | CLIA Kit for Cluster Of Differentiation 7 (CD7) | CLIA assay for Antigen Detection |
| ELV056Mo01 | ELISA Kit for Cluster Of Differentiation 7 (CD7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system."
EMBO J. 6:3313-3316(1987) [PubMed] [Europe PMC] [Abstract]
"Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene."
Proc. Natl. Acad. Sci. U.S.A. 88:603-607(1991) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of the gene coding for the human T cell differentiation antigen CD7."
Immunogenetics 33:352-360(1991) [PubMed] [Europe PMC] [Abstract]
"Characterization of the surface topography and putative tertiary structure of the human CD7 molecule."
J. Immunol. 143:3632-3640(1989) [PubMed] [Europe PMC] [Abstract]
"Identification of CD7 as a cognate of the human K12 (SECTM1) protein."
J. Biol. Chem. 275:3431-3437(2000) [PubMed] [Europe PMC] [Abstract]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]