Formyl Peptide Receptor 2 (FPR2)
LXA4R; FPRL1; RFP; ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; HM63; LRLP; N-Formyl Peptide Receptor 2; Lipoxin A4 Receptor Like Protein; FMLP-related receptor I
LXA4R, which was first identified based on sequence homology as the formyl peptide receptor like receptor (FPRL1). Lipoxin signaling through the LXA4R inhibits chemotaxis, transmigration, superoxide generation and NF-kappa B activation. Bao et al. (1992) identified 2 structural homologs of formyl peptide receptor (FPR1), FPRL1 (FPR2) and FPRL2 (FPR3). Since these 2 structural homologs did not recognize the ligand FMLP,
Bao et al. (1992) referred to them as orphan receptors. Nonetheless, they probably function as chemotactic receptors.Prat et al. (2006) found that a Staphylococcus aureus protein, which they called FLIPr, bound to and impaired neutrophil responses to FPRL1 agonists in terms of calcium mobilization and directed migration.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Hu01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Hu01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Hu01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Hu01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Hu01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Mu01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Mu01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Mu01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Mu01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Mu01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Ra01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Ra01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Ra01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Ra01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Ra01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Ca01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Ca01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Ca01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Ca01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Ca01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Po01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Po01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Po01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Po01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Po01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Bo01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Bo01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Bo01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Bo01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Bo01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Rb01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Rb01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Rb01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Rb01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Rb01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU927Mo01 | Recombinant Formyl Peptide Receptor 2 (FPR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU927Mo01 | Monoclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IP. |
| PAU927Mo01 | Polyclonal Antibody to Formyl Peptide Receptor 2 (FPR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU927Mo01 | CLIA Kit for Formyl Peptide Receptor 2 (FPR2) | CLIA assay for Antigen Detection |
| ELU927Mo01 | ELISA Kit for Formyl Peptide Receptor 2 (FPR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19."
Genomics 13:437-440(1992) [PubMed] [Europe PMC] [Abstract]
"Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils."
Gene 118:303-304(1992) [PubMed] [Europe PMC] [Abstract]
"Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor."
Biochem. Biophys. Res. Commun. 184:582-589(1992) [PubMed] [Europe PMC] [Abstract]
"A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family."
J. Biol. Chem. 267:7637-7643(1992) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors."
Int. Immunol. 5:1239-1249(1993) [PubMed] [Europe PMC] [Abstract]
"Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release."
J. Exp. Med. 187:1285-1294(1998) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors."
J. Exp. Med. 185:1693-1704(1997) [PubMed] [Europe PMC] [Abstract]