Dynamin 1 (DNM1)
Dynamin-1 is a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity.
More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Hu01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Hu01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Hu01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Hu01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Hu01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Mu01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Mu01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Mu01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Mu01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Mu01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Ra01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Ra01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Ra01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Ra01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Ra01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Ca01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Ca01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Ca01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Ca01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Ca01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Po01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Po01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Po01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Po01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Po01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Bo01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Bo01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Bo01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Bo01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Bo01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Rb01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Rb01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Rb01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Rb01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Rb01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU880Mo01 | Recombinant Dynamin 1 (DNM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU880Mo01 | Monoclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IP. |
| PAU880Mo01 | Polyclonal Antibody to Dynamin 1 (DNM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU880Mo01 | CLIA Kit for Dynamin 1 (DNM1) | CLIA assay for Antigen Detection |
| ELU880Mo01 | ELISA Kit for Dynamin 1 (DNM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Mutations in human dynamin block an intermediate stage in coated vesicle formation."
J. Cell Biol. 122:553-563(1993) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis."
Mol. Biol. Cell 16:2058-2067(2005) [PubMed] [Europe PMC] [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
"Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis."
FEBS Lett. 581:644-650(2007) [PubMed] [Europe PMC] [Abstract]
"A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein."
J. Biol. Chem. 283:14257-14268(2008) [PubMed] [Europe PMC] [Abstract]
"Phosphoproteome of resting human platelets."
J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Three-dimensional solution structure of the pleckstrin homology domain from dynamin."
Curr. Biol. 4:884-891(1994) [PubMed] [Europe PMC] [Abstract]
"Crystal structure at 2.2-A resolution of the pleckstrin homology domain from human dynamin."
Cell 79:199-209(1994) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of the pleckstrin homology domain from dynamin."
Nat. Struct. Biol. 1:782-788(1994) [PubMed] [Europe PMC] [Abstract]