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S100 Calcium Binding Protein A4 (S100A4)

S100-A4; MTS1; 18A2; 42A; CAPL; P9KA; PEL98; Calcium protein; Calvasculin; Metastasin; Protein Mts1; Placental calcium-binding protein; Murine placental homolog

S100 calcium binding protein A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.

This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Hu01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Hu01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Hu01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Hu01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Hu01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Mu01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Mu01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Mu01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Mu01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Mu01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Ra01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Ra01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Ra01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Ra01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Ra01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Ca01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Ca01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Ca01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Ca01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Ca01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Po01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Po01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Po01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Po01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Po01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Bo01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Bo01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Bo01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Bo01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Bo01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Rb01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Rb01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Rb01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Rb01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Rb01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU823Mo01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU823Mo01 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
PAU823Mo01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
Assay Kits CLU823Mo01 CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA assay for Antigen Detection
ELU823Mo01 ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart."
Biochemistry 31:10258-10264(1992) [PubMed] [Europe PMC] [Abstract]

"Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E."
Proc. Natl. Acad. Sci. U.S.A. 90:6547-6551(1993) [PubMed] [Europe PMC] [Abstract]

"Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences."
Proc. Natl. Acad. Sci. U.S.A. 89:9146-9150(1992) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Calcyclin and calvasculin exist in human platelets."
Biochem. Biophys. Res. Commun. 189:1310-1316(1992) [PubMed] [Europe PMC] [Abstract]

"Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)."
J. Biol. Chem. 277:5229-5235(2002) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy."
Biochemistry 41:12670-12680(2002) [PubMed] [Europe PMC] [Abstract]