Glucose Transporter 4 (GLUT4)
SLC2A4; Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive
GLUT4 is the insulin-regulated glucose transporter found in adipose tissues and striated muscle (skeletal and cardiac) that is responsible for insulin-regulated glucose disposal.In the absence of insulin, GLUT4 is sequestered in the interior of muscle and fat cells within lipid bilayers of vesicles. Insulin induces the translocation of GLUT4 from intracellular storage sites to the plasma membrane. Insulin binds to the insulin receptor in its dimeric form.
The receptor phosphorylates and subsequently activates IRS-1, which converts PIP2 to PIP3. PIP3 is bound to PKB (protein kinase B), signaling for PDK1 to phosphorylate PKB. Once phosphorylated, PKB is in its active form and phosphorylates other targets that stimulate GLUT4 to be expressed on the plasma membrane.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Hu01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Hu01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Hu01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Hu01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Hu01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Mu01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Mu01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Mu01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Mu01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Mu01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Ra01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Ra01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Ra01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Ra01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Ra01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Ca01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Ca01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Ca01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Ca01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Ca01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Po01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Po01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Po01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Po01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Po01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Bo01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Bo01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Bo01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Bo01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Bo01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Rb01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Rb01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Rb01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Rb01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Rb01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU820Mo01 | Recombinant Glucose Transporter 4 (GLUT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU820Mo01 | Monoclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IP. |
| PAU820Mo01 | Polyclonal Antibody to Glucose Transporter 4 (GLUT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU820Mo01 | CLIA Kit for Glucose Transporter 4 (GLUT4) | CLIA assay for Antigen Detection |
| ELU820Mo01 | ELISA Kit for Glucose Transporter 4 (GLUT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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