Call Now

S100 Calcium Binding Protein A7 (S100A7)

S100-A7; PSOR1; S100A7c; Psoriasin 1

S100 calcium binding protein A7 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.

This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The protein functions as a prominent antimicrobial peptide mainly against E. coli.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Hu01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Hu01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Hu01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Hu01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Hu01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Mu01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Mu01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Mu01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Mu01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Mu01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Ra01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Ra01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Ra01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Ra01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Ra01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Ca01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Ca01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Ca01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Ca01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Ca01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Po01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Po01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Po01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Po01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Po01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Bo01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Bo01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Bo01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Bo01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Bo01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Rb01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Rb01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Rb01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Rb01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Rb01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU808Mo01 Recombinant S100 Calcium Binding Protein A7 (S100A7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU808Mo01 Monoclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IP.
PAU808Mo01 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) WB; IHC; ICC; IF.
Assay Kits CLU808Mo01 CLIA Kit for S100 Calcium Binding Protein A7 (S100A7) CLIA assay for Antigen Detection
ELU808Mo01 ELISA Kit for S100 Calcium Binding Protein A7 (S100A7) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Molecular cloning, occurrence, and expression of a novel partially secreted protein 'psoriasin' that is highly up-regulated in psoriatic skin."
J. Invest. Dermatol. 97:701-712(1991) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Amino acid sequence analysis of human S100A7 (psoriasin) by tandem mass spectrometry."
Biochem. Biophys. Res. Commun. 217:257-263(1995) [PubMed] [Europe PMC] [Abstract]

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Electrophoresis 13:960-969(1992) [PubMed] [Europe PMC] [Abstract]

"Bladder squamous cell carcinomas express psoriasin and externalize it to the urine."
J. Urol. 155:2105-2112(1996) [PubMed] [Europe PMC] [Abstract]

"RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer."
BMC Cancer 2:28-28(2002) [PubMed] [Europe PMC] [Abstract]

"Genomic and phylogenetic analysis of the S100A7 (psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21."
J. Mol. Evol. 56:397-406(2003) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing."
Structure 6:477-489(1998) [PubMed] [Europe PMC] [Abstract]

"Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states."
Biochemistry 38:1695-1704(1999) [PubMed] [Europe PMC] [Abstract]