Interleukin 20 (IL20)
IL10D; IL10-D; ZCYTO10; Cytokine Zcyto10
Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin.
In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.The 176-amino acid IL20 protein contains 6 conserved cysteine residues and shares 76% amino acid identity with its murine counterpart. Based on amino acid identities, IL20 is most homologous to 3 members of the IL10 family, IL19 , MDA7 , and IL10.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Hu01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Hu01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Hu01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Hu01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Hu01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Mu01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Mu01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Mu01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Mu01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Mu01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Ra01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Ra01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Ra01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Ra01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Ra01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Ca01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Ca01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Ca01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Ca01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Ca01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Po01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Po01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Po01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Po01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Po01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Bo01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Bo01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Bo01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Bo01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Bo01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Rb01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Rb01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Rb01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Rb01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Rb01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU786Mo01 | Recombinant Interleukin 20 (IL20) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU786Mo01 | Monoclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IP. |
| PAU786Mo01 | Polyclonal Antibody to Interleukin 20 (IL20) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU786Mo01 | CLIA Kit for Interleukin 20 (IL20) | CLIA assay for Antigen Detection |
| ELU786Mo01 | ELISA Kit for Interleukin 20 (IL20) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Interleukin 20: discovery, receptor identification, and role in epidermal function."
Cell 104:9-19(2001) [PubMed] [Europe PMC] [Abstract]
"Interleukin-20 promotes angiogenesis in a direct and indirect manner."
Genes Immun. 7:234-242(2006) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
"Tissue microarray analysis of interleukin-20 expression."
Cytokine 35:44-52(2006) [PubMed] [Europe PMC] [Abstract]
"Ultraviolet B light stimulates interleukin-20 expression by human epithelial keratinocytes."
Photochem. Photobiol. 82:1292-1300(2006) [PubMed] [Europe PMC] [Abstract]
"Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines."
Proc. Natl. Acad. Sci. U.S.A. 109:12704-12709(2012) [PubMed] [Europe PMC] [Abstract]