Asialoglycoprotein Receptor 2 (ASGR2)
CLEC4H2; Asialoglyco Protein Receptor 2; C-type lectin domain family 4 member H2; Hepatic lectin H2
The ASGR2 gene encodes a glycoprotein that forms the asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells (Spiess and Lodish, 1985).From the same cDNA library that was made from the human hepatoma cell line HepG2 and was used to isolate ASGR1, Spiess and Lodish (1985) isolated and sequenced a clone encoding a second asialoglycoprotein receptor, which they referred to as H2 and which had protein sequence homology of 58% to H1.
The rat similarly has 2 ASG receptors, R1 and R2. Spiess and Lodish (1985) found that H1 is more homologous to R1 than to H2, and H2 is more homologous to R2 than to H1.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Hu01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Hu01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Hu01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Hu01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Hu01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Mu01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Mu01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Mu01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Mu01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Mu01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Ra01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Ra01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Ra01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Ra01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Ra01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Ca01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Ca01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Ca01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Ca01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Ca01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Po01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Po01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Po01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Po01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Po01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Bo01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Bo01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Bo01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Bo01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Bo01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Rb01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Rb01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Rb01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Rb01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Rb01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU777Mo01 | Recombinant Asialoglycoprotein Receptor 2 (ASGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU777Mo01 | Monoclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IP. |
| PAU777Mo01 | Polyclonal Antibody to Asialoglycoprotein Receptor 2 (ASGR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU777Mo01 | CLIA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | CLIA assay for Antigen Detection |
| ELU777Mo01 | ELISA Kit for Asialoglycoprotein Receptor 2 (ASGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution."
Proc. Natl. Acad. Sci. U.S.A. 82:6465-6469(1985) [PubMed] [Europe PMC] [Abstract]
"Differences in the abundance of variably spliced transcripts for the second asialoglycoprotein receptor polypeptide, H2, in normal and transformed human liver."
Hepatology 15:395-402(1992) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
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