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VEGF Co Regulated Chemokine 1 (VCC1)

CXCL17; SCYB17; DMC; Chemokine C-X-C-Motif Ligand 7; Dendritic cell and monocyte chemokine-like protein

CXCL17 is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC).

This chemokine is constitutively expressed in the lung.The predicted 119-amino acid protein has a calculated molecular mass of 13.8 kD and shares 71% identity with its mouse homolog. DMC has an N-terminal signal peptide, but no N-glycosylation sites. Secondary structure analysis showed highest similarity to CXCL8 (IL8), whereas circular dichroism analysis revealed that active, purified DMC adopted a secondary structure resembling that of CCL5  and CCL4.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Hu01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Hu01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Hu01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Hu01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Hu01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Mu01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Mu01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Mu01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Mu01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Mu01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Ra01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Ra01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Ra01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Ra01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Ra01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Ca01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Ca01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Ca01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Ca01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Ca01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Po01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Po01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Po01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Po01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Po01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Bo01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Bo01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Bo01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Bo01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Bo01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Rb01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Rb01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Rb01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Rb01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Rb01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU776Mo01 Recombinant VEGF Co Regulated Chemokine 1 (VCC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU776Mo01 Monoclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IP.
PAU776Mo01 Polyclonal Antibody to VEGF Co Regulated Chemokine 1 (VCC1) WB; IHC; ICC; IF.
Assay Kits CLU776Mo01 CLIA Kit for VEGF Co Regulated Chemokine 1 (VCC1) CLIA assay for Antigen Detection
ELU776Mo01 ELISA Kit for VEGF Co Regulated Chemokine 1 (VCC1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"VCC-1, a novel chemokine, promotes tumor growth."
Biochem. Biophys. Res. Commun. 350:74-81(2006) [PubMed] [Europe PMC] [Abstract]

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods."
J. Immunol. 176:2069-2073(2006) [PubMed] [Europe PMC] [Abstract]

"Broad up-regulation of innate defense factors during acute cholera."
Infect. Immun. 75:2343-2350(2007) [PubMed] [Europe PMC] [Abstract]