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Bone Morphogenetic Protein 10 (BMP10)

SPN U738
HGNC 20869
MGI 1338820
PubMed 10072785
RGD 1562986
UniProt O95393
Wiki BMP10

Bone morphogenetic protein 10 (BMP10) is a polypeptide belonging to the TGF-beta superfamily of proteins.It is a novel protein that, unlike most other BMP's, is likely to be involved in the tabeculation of the heart. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP10 is categorized as a BMP since it shares a large sequence homology with other BMP's in the TGF-beta superfamily.

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Inhibits endothelial cell migration and growth.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Hu01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Hu01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Hu01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Hu01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Hu01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Mu01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Mu01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Mu01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Mu01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Mu01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Ra01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Ra01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Ra01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Ra01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Ra01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Ca01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Ca01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Ca01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Ca01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Ca01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Po01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Po01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Po01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Po01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Po01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Bo01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Bo01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Bo01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Bo01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Bo01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Rb01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Rb01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Rb01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Rb01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Rb01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU738Mo01 Recombinant Bone Morphogenetic Protein 10 (BMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU738Mo01 Monoclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IP.
PAU738Mo01 Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10) WB; IHC; ICC; IF.
Assay Kits CLU738Mo01 CLIA Kit for Bone Morphogenetic Protein 10 (BMP10) CLIA assay for Antigen Detection
ELU738Mo01 ELISA Kit for Bone Morphogenetic Protein 10 (BMP10) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses."
J. Biol. Chem. 280:32122-32132(2005) [PubMed] [Europe PMC] [Abstract]

"Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells."
Blood 109:1953-1961(2007) [PubMed] [Europe PMC] [Abstract]

"Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer."
Cancer Sci. 101:2137-2144(2010) [PubMed] [Europe PMC] [Abstract]

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