Amphiphysin (AMPH)
AMPH1; Stiff-Man Syndrome With Breast Cancer 128kDa Autoantigen
Amphiphysin is a brain-enriched protein with an N-terminal lipid interaction, dimerisation and membrane bending BAR domain, a middle clathrin and adaptor binding domain and a C-terminal SH3 domain. In the brain, its primary function is thought to be the recruitment of dynamin to sites of clathrin-mediated endocytosis.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Hu01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Hu01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Hu01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Hu01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Hu01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Mu01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Mu01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Mu01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Mu01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Mu01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Ra01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Ra01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Ra01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Ra01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Ra01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Ca01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Ca01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Ca01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Ca01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Ca01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Po01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Po01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Po01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Po01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Po01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Bo01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Bo01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Bo01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Bo01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Bo01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Rb01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Rb01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Rb01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Rb01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Rb01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU639Mo01 | Recombinant Amphiphysin (AMPH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU639Mo01 | Monoclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IP. |
| PAU639Mo01 | Polyclonal Antibody to Amphiphysin (AMPH) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU639Mo01 | CLIA Kit for Amphiphysin (AMPH) | CLIA assay for Antigen Detection |
| ELU639Mo01 | ELISA Kit for Amphiphysin (AMPH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Autoimmunity in stiff-man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161."
FEBS Lett. 351:73-79(1994) [PubMed] [Europe PMC] [Abstract]
"Primary structure of human amphiphysin, the dominant autoantigen of paraneoplastic stiff-man syndrome, and mapping of its gene (AMPH) to chromosome 7p13-p14."
Hum. Mol. Genet. 4:265-268(1995) [PubMed] [Europe PMC] [Abstract]
"Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer."
Mol. Med. 4:29-39(1998) [PubMed] [Europe PMC] [Abstract]
"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly."
PLoS Biol. 4:E262-E262(2006) [PubMed] [Europe PMC] [Abstract]
"Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits."
Biochem. Biophys. Res. Commun. 402:408-413(2010) [PubMed] [Europe PMC] [Abstract]
"Accessory protein recruitment motifs in clathrin-mediated endocytosis."
Structure 10:797-809(2002) [PubMed] [Europe PMC] [Abstract]