Carnitine Acetyltransferase (CRAT)
CAT1; Carnitine O-Acetyltransferase; Carnitine acetylase
Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments.
Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Hu01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Hu01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Hu01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Hu01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Hu01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Mu01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Mu01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Mu01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Mu01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Mu01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Ra01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Ra01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Ra01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Ra01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Ra01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Ca01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Ca01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Ca01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Ca01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Ca01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Po01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Po01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Po01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Po01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Po01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Bo01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Bo01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Bo01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Bo01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Bo01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Rb01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Rb01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Rb01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Rb01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Rb01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU448Mo01 | Recombinant Carnitine Acetyltransferase (CRAT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU448Mo01 | Monoclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IP. |
| PAU448Mo01 | Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU448Mo01 | CLIA Kit for Carnitine Acetyltransferase (CRAT) | CLIA assay for Antigen Detection |
| ELU448Mo01 | ELISA Kit for Carnitine Acetyltransferase (CRAT) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Divergent sequences in the 5' region of cDNA suggest alternative splicing as a mechanism for the generation of carnitine acetyltransferases with different subcellular localizations."
Biochem. J. 303:37-41(1994) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of cDNAs encoding human carnitine acetyltransferase and mapping of the corresponding gene to chromosome 9q34.1."
Genomics 23:94-99(1994) [PubMed] [Europe PMC] [Abstract]
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Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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