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Flotillin 2 (FLOT2)

ECS1; ESA; ESA1; M17S1; Epidermal Surface Antigen 1; Membrane Component,Chromosome 17,Surface Marker 1; 35kD Protein Identified By Monoclonal Antibody ECS-1

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Flotillin-2 is a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.
Human epidermal surface antigen-1 was identified as a 35-kD antigen by means of a mouse monoclonal antibody raised against human keratinocytes. The monoclonal antibody was found to cause keratinocyte dissociation in vitro; hence, the conclusion that the native protein is involved in cell adhesion. The mouse and human 5-prime- and 3-prime untranslated sequences are conserved. Similar RNA folding patterns of the 5-prime untranslated region are predicted despite a 91-bp insertion in the mouse.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Hu01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Hu01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Hu01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Hu01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Hu01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Mu01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Mu01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Mu01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Mu01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Mu01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Ra01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Ra01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Ra01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Ra01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Ra01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Ca01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Ca01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Ca01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Ca01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Ca01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Po01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Po01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Po01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Po01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Po01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Bo01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Bo01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Bo01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Bo01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Bo01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Rb01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Rb01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Rb01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Rb01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Rb01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU368Mo01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU368Mo01 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
PAU368Mo01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IF.
Assay Kits CLU368Mo01 CLIA Kit for Flotillin 2 (FLOT2) CLIA assay for Antigen Detection
ELU368Mo01 ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

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J. Biol. Chem. 285:31616-31633(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells."
J. Biol. Chem. 287:523-530(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]