Nephronophthisis 2, Infantile (NPHP2)
INVS; NPH2; INV; Inversin; Nephrocystin 2; Inversion of embryo turning homolog
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Hu01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Hu01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Hu01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Hu01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Hu01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Mu01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Mu01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Mu01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Mu01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Mu01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Ra01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Ra01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Ra01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Ra01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Ra01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Ca01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Ca01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Ca01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Ca01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Ca01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Po01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Po01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Po01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Po01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Po01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Bo01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Bo01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Bo01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Bo01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Bo01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Rb01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Rb01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Rb01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Rb01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Rb01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU304Mo01 | Recombinant Nephronophthisis 2, Infantile (NPHP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU304Mo01 | Monoclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IP. |
| PAU304Mo01 | Polyclonal Antibody to Nephronophthisis 2, Infantile (NPHP2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU304Mo01 | CLIA Kit for Nephronophthisis 2, Infantile (NPHP2) | CLIA assay for Antigen Detection |
| ELU304Mo01 | ELISA Kit for Nephronophthisis 2, Infantile (NPHP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification, genomic organization, chromosomal mapping and mutation analysis of the human INV gene, the ortholog of a murine gene implicated in left-right axis development and biliary atresia."
Hum. Genet. 110:157-165(2002) [PubMed] [Europe PMC] [Abstract]
"The left-right determinant inversin has highly conserved ankyrin repeat and IQ domains and interacts with calmodulin."
Hum. Genet. 110:377-384(2002) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination."
Nat. Genet. 34:413-420(2003) [PubMed] [Europe PMC] [Abstract]
"Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways."
Nat. Genet. 37:537-543(2005) [PubMed] [Europe PMC] [Abstract]
"Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia."
Am. J. Hum. Genet. 82:959-970(2008) [PubMed] [Europe PMC] [Abstract]
"Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways."
Cell 145:513-528(2011) [PubMed] [Europe PMC] [Abstract]
"ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3."
Nat. Genet. 45:951-956(2013) [PubMed] [Europe PMC] [Abstract]