Lysophosphatidic Acid Receptor 1 (LPAR1)
EDG2; Gpcr26; LPA1; Mrec1.3; edg-2; rec.1.3; vzg-1; Endothelial Differentiation,Lysophosphatidic Acid G-Protein-Coupled Receptor 2
Lysophosphatidic acid receptor 1 is a G protein-coupled receptor which binds the lipid signaling molecule lysophosphatidic acid (LPA). Hence this receptor is also known as LPA1.The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Alternative splicing of this gene has been observed and two transcript variants have been described, each encoding identical proteins.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Hu01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Hu01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Hu01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Hu01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Hu01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Mu01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Mu01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Mu01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Mu01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Mu01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Ra01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Ra01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Ra01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Ra01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Ra01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Ca01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Ca01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Ca01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Ca01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Ca01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Po01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Po01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Po01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Po01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Po01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Bo01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Bo01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Bo01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Bo01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Bo01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Rb01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Rb01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Rb01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Rb01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Rb01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU280Mo01 | Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU280Mo01 | Monoclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IP. |
| PAU280Mo01 | Polyclonal Antibody to Lysophosphatidic Acid Receptor 1 (LPAR1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU280Mo01 | CLIA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | CLIA assay for Antigen Detection |
| ELU280Mo01 | ELISA Kit for Lysophosphatidic Acid Receptor 1 (LPAR1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Biochem. Biophys. Res. Commun. 231:619-622(1997) [PubMed] [Europe PMC] [Abstract]
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"Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK."
Cell. Signal. 21:1207-1217(2009) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]